Reformulating lipid nanoparticles for organ-targeted mRNA accumulation and translation
Kexin Su, Lu Shi, Tao Sheng et al. · Nature Communications · 2024
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Biochemistry, Genetics and Molecular Biology
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Antibiotic action and resistance: updated review of mechanisms, spread, influencing factors, and alternative approaches for combating resistance
Esraa M. Halawa, Mohamed Fadel, Mohammed W. Al-Rabia et al. · Frontiers in Pharmacology · 2024 · Review
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De novo variants in the RNU4-2 snRNA cause a frequent neurodevelopmental syndrome
Yuyang Chen, Ruebena Dawes, Hyung Chul Kim et al. · Nature · 2024
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SQANTI3: curation of long-read transcriptomes for accurate identification of known and novel isoforms
Francisco J. Pardo-Palacios, Angeles Arzalluz-Luque, Liudmyla Kondratova et al. · Nature Methods · 2024
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PANoptosis: bridging apoptosis, pyroptosis, and necroptosis in cancer progression and treatment
Jie Gao, Anying Xiong, Jiliu Liu et al. · Cancer Gene Therapy · 2024 · Review
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Advances in myocardial energy metabolism: metabolic remodelling in heart failure and beyond
Qiuyu Sun, Qutuba G Karwi, Nathan Wong et al. · Cardiovascular Research · 2024 · Review
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Designed endocytosis-inducing proteins degrade targets and amplify signals
Buwei Huang, Mohamad Abedi, Green Ahn et al. · Nature · 2024
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Genetic drivers of heterogeneity in type 2 diabetes pathophysiology
Ken Suzuki, Konstantinos Hatzikotoulas, Lorraine Southam et al. · Nature · 2024
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The Complex Role of Matrix Metalloproteinase-2 (MMP-2) in Health and Disease
Marta Wolosowicz, Slawomir Prokopiuk, Tomasz W. Kaminski · International Journal of Molecular Sciences · 2024 · Review
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Host genetic regulation of human gut microbial structural variation
Daria V. Zhernakova, Daoming Wang, Lei Liu et al. · Nature · 2024 · Meta-analysis
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Induced pluripotent stem cells (iPSCs): molecular mechanisms of induction and applications
Jonas Cerneckis, Hongxia Cai, Yanhong Shi · Signal Transduction and Targeted Therapy · 2024 · Review
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Paternal microbiome perturbations impact offspring fitness
Ayele Argaw-Denboba, Thomas S. B. Schmidt, Monica Di Giacomo et al. · Nature · 2024
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General Overview of Klebsiella pneumonia: Epidemiology and the Role of Siderophores in Its Pathogenicity
Rim Abbas, Mohamed Chakkour, Hiba Zein El Dine et al. · Biology · 2024 · Review
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Protein language models learn evolutionary statistics of interacting sequence motifs
Zhidian Zhang, Hannah K. Wayment-Steele, Garyk Brixi et al. · Proceedings of the National Academy of Sciences · 2024
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Inflammasomes in chronic liver disease: Hepatic injury, fibrosis progression and systemic inflammation
Vlad Taru, Gyongyi Szabo, Wajahat Mehal et al. · Journal of Hepatology · 2024 · Review
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Inter-plasmid transfer of antibiotic resistance genes accelerates antibiotic resistance in bacterial pathogens
Xiaolong Wang, Hanhui Zhang, Shenbo Yu et al. · The ISME Journal · 2024
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Leveraging functional genomic annotations and genome coverage to improve polygenic prediction of complex traits within and between ancestries
Zhili Zheng, Shouye Liu, Julia Sidorenko et al. · Nature Genetics · 2024
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Dietary fibre directs microbial tryptophan metabolism via metabolic interactions in the gut microbiota
Anurag K. Sinha, Martin F. Laursen, Julius E. Brinck et al. · Nature Microbiology · 2024
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A compendium of genetic regulatory effects across pig tissues
Jinyan Teng, Yahui Gao, Hongwei Yin et al. · Nature Genetics · 2024
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Next-generation probiotics: the upcoming biotherapeutics
Omnia Momtaz Al-Fakhrany, Engy Elekhnawy · Molecular Biology Reports · 2024 · Review
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