Changing paradigm through a genome-based approach to clinical and basic immunology

Genomics or, in other words, genome-based biology offers an entirely new prospective on strategies applicable to the study of distinct physio-pathological conditions through a discovery-driven approach that may complement traditional hypothesis-driven scientific thinking. Indeed, analysis of genomic variation at the DNA level and functional genomics that addresses transcriptional variations of biological material have been extensively used by bio-scientists to study distinct pathological conditions and this trend has spread, more recently to applications in basic and clinical immunology. This shift in paradigm in the study of biology and, for the purpose of this commentary, in immunology may very well be suitable for the understanding of immune regulation in sickness and in health which represents a particularly complicated biological matter due do the extreme versatility of the immune system in adaptation to environmental changes.

Abstract licence: CC BY-NC-ND

1. 15.

   GoMiner: a resource for biological interpretation of genomic and proteomic data · 2003

17 more references, whose wording the paper’s licence keeps private.

A person counts once a day per paper. We keep no cookie and no address: a reader is a hash that changes every day. Any month under five reads shows no number.