Role of Hydrogen Sulfide in Ischemia-Reperfusion Injury

Abstract

Ischemia-reperfusion (I/R) injury is one of the major causes of high morbidity, disability, and mortality in the world. I/R injury remains a complicated and unresolved situation in clinical practice, especially in the field of solid organ transplantation. Hydrogen sulfide (H 2 S) is the third gaseous signaling molecule and plays a broad range of physiological and pathophysiological roles in mammals. H 2 S could protect against I/R injury in many organs and tissues, such as heart, liver, kidney, brain, intestine, stomach, hind-limb, lung, and retina. The goal of this review is to highlight recent findings regarding the role of H 2 S in I/R injury. In this review, we present the production and metabolism of H 2 S and further discuss the effect and mechanism of H 2 S in I/R injury.

References 191

1. 1.

   Eltzschig H. K., Eckle T. Ischemia and reperfusion—from mechanism to translation. Nature Medicine. 2011;17(11):1391-1401.

   Not in our library10.1038/nm.2507

2. 2.

   Duehrkop C., Rieben R. Ischemia/reperfusion injury: effect of simultaneous inhibition of plasma cascade systems versus specific complement inhibition. Biochemical Pharmacology. 2014;88(1):12-22.

   Not in our library10.1016/j.bcp.2013.12.013

3. 3.

   Jennings R. B. Historical perspective on the pathology of myocardial ischemia/reperfusion injury. Circulation Research. 2013;113(4):428-438.

   Not in our library10.1161/circresaha.113.300987

4. 4.

   Hausenloy D. J., Yellon D. M. The therapeutic potential of ischemic conditioning: an update. Nature Reviews Cardiology. 2011;8(11):619-629.

   Not in our library10.1038/nrcardio.2011.85

5. 5.

   Heusch G., Libby P., Gersh B., et al. Cardiovascular remodelling in coronary artery disease and heart failure. The Lancet. 2014;383(9932):1933-1943.

   Not in our library10.1016/s0140-6736(14)60107-0

6. 6.

   Andreadou I., Iliodromitis E. K., Rassaf T., Schulz R., Papapetropoulos A., Ferdinandy P. The role of gasotransmitters NO, H2S and CO in myocardial ischaemia/reperfusion injury and cardioprotection by preconditioning, postconditioning and remote conditioning. British Journal of Pharmacology. 2014.

   Not in our library10.1111/bph.12811

7. 7.

   Kolluru G. K., Shen X., Bir S. C., Kevil C. G. Hydrogen sulfide chemical biology: pathophysiological roles and detection. Nitric Oxide: Biology and Chemistry. 2013;35:5-20.

   Not in our library10.1016/j.niox.2013.07.002

8. 8.

   Li Q., Lancaster J. R. Chemical foundations of hydrogen sulfide biology. Nitric Oxide—Biology and Chemistry. 2013;35:21-34.

   Not in our library10.1016/j.niox.2013.07.001

9. 9.

   Kimura H. The physiological role of hydrogen sulfide and beyond. Nitric Oxide - Biology and Chemistry. 2014;41:4-10.

   Not in our library10.1016/j.niox.2014.01.002

10. 10.
    Redox biology of hydrogen sulfide: Implications for physiology, pathophysiology, and pharmacology · 2013

    No notice
11. 11.

    Papapetropoulos A., Pyriochoua A., Altaany Z., et al. Hydrogen sulfide is an endogenous stimulator of angiogenesis. Proceedings of the National Academy of Sciences of the United States of America. 2009;106(51):21972-21977.

    Not in our library10.1073/pnas.0908047106

12. 12.

    Yang G., Wu L., Jiang B., et al. H2S as a physiologic vasorelaxant: hypertension in mice with deletion of cystathionine γ-lyase. Science. 2008;322(5901):587-590.

    Not in our library10.1126/science.1162667

13. 13.

    Xue R., Hao D.-D., Sun J.-P., et al. Hydrogen sulfide treatment promotes glucose uptake by increasing insulin receptor sensitivity and ameliorates kidney lesions in type 2 diabetes. Antioxidants and Redox Signaling. 2013;19(1):5-23.

    Not in our library10.1089/ars.2012.5024

14. 14.

    Bos E. M., Wang R., Snijder P. M., et al. Cystathionine γ-lyase protects against renal ischemia/reperfusion by modulating oxidative stress. Journal of the American Society of Nephrology. 2013;24(5):759-770.

    Not in our library10.1681/asn.2012030268

15. 15.

    Calvert J. W., Elston M., Nicholson C. K., et al. Genetic and pharmacologic hydrogen sulfide therapy attenuates ischemia-induced heart failure in mice. Circulation. 2010;122(1):11-19.

    Not in our library10.1161/circulationaha.109.920991

16. 16.

    Fu Z., Liu X., Geng B., Fang L., Tang C. Hydrogen sulfide protects rat lung from ischemia-reperfusion injury. Life Sciences. 2008;82(23-24):1196-1202.

    Not in our library10.1016/j.lfs.2008.04.005

17. 17.

    Wang D., Ma Y., Li Z., et al. The role of AKT1 and autophagy in the protective effect of hydrogen sulphide against hepatic ischemia/reperfusion injury in mice. Autophagy. 2012;8(6):954-962.

    Not in our library10.4161/auto.19927

18. 18.

    Yin J., Tu C., Zhao J., et al. Exogenous hydrogen sulfide protects against global cerebral ischemia/reperfusion injury via its anti-oxidative, anti-inflammatory and anti-apoptotic effects in rats. Brain Research. 2013;1491:188-196.

    Not in our library10.1016/j.brainres.2012.10.046

19. 19.

    lo Faro M. L., Fox B., Whatmore J. L., et al. Hydrogen sulfide and nitric oxide interactions in inflammation. Nitric Oxide. 2014;41:38-47.

    Not in our library10.1016/j.niox.2014.05.014

20. 20.

    Collman J. P., Ghosh S., Dey A., Decréau R. A. Using a functional enzyme model to understand the chemistry behind hydrogen sulfide induced hibernation. Proceedings of the National Academy of Sciences of the United States of America. 2009;106(52):22090-22095.

    Not in our library10.1073/pnas.0904082106

21. 21.

    Ríos-González B. B., Román-Morales E. M., Pietri R., López-Garriga J. Hydrogen sulfide activation in hemeproteins: the sulfheme scenario. Journal of Inorganic Biochemistry. 2014;133:78-86.

    Not in our library10.1016/j.jinorgbio.2014.01.013

22. 22.

    Pietri R., Román-Morales E., López-Garriga J. Hydrogen sulfide and hemeproteins: knowledge and mysteries. Antioxidants and Redox Signaling. 2011;15(2):393-404.

    Not in our library10.1089/ars.2010.3698

23. 23.

    Hourihan J. M., Kenna J. G., Hayes J. D. The gasotransmitter hydrogen sulfide induces Nrf2-target genes by inactivating the keap1 ubiquitin ligase substrate adaptor through formation of a disulfide bond between Cys-226 and Cys-613. Antioxidants and Redox Signaling. 2013;19(5):465-481.

    Not in our library10.1089/ars.2012.4944

24. 24.

    Jiang B., Tang G., Cao K., Wu L., Wang R. Molecular mechanism for H2S-induced activation of KATP channels. Antioxidants and Redox Signaling. 2010;12(10):1167-1178.

    Not in our library10.1089/ars.2009.2894

25. 25.

    Ge S.-N., Zhao M.-M., Wu D.-D., et al. Hydrogen sulfide targets EGFR Cys797/Cys798 residues to induce Na+/K+-ATPase endocytosis and inhibition in renal tubular epithelial cells and increase sodium excretion in chronic salt-loaded rats. Antioxidants & Redox Signaling. 2014;21(15):2061-2082.

    Not in our library10.1089/ars.2013.5304

26. 26.

    Tao B.-B., Liu S.-Y., Zhang C.-C., et al. VEGFR2 functions as an H2S-targeting receptor protein kinase with its novel Cys1045-Cys1024 disulfide bond serving as a specific molecular switch for hydrogen sulfide actions in vascular endothelial cells. Antioxidants and Redox Signaling. 2013;19(5):448-464.

    Not in our library10.1089/ars.2012.4565

27. 27.

    Polhemus D. J., Lefer D. J. Emergence of hydrogen sulfide as an endogenous gaseous signaling molecule in cardiovascular disease. Circulation Research. 2014;114(4):730-737.

    Not in our library10.1161/circresaha.114.300505

28. 28.

    Shibuya N., Mikami Y., Kimura Y., Nagahara N., Kimura H. Vascular endothelium expresses 3-mercaptopyruvate sulfurtransferase and produces hydrogen sulfide. Journal of Biochemistry. 2009;146(5):623-626.

    Not in our library10.1093/jb/mvp111

29. 29.

    Shibuya N., Koike S., Tanaka M., et al. A novel pathway for the production of hydrogen sulfide from D-cysteine in mammalian cells. Nature Communications. 2013;4, article 1366.

    Not in our library10.1038/ncomms2371

30. 30.

    Kimura H. Production and physiological effects of hydrogen sulfide. Antioxidants and Redox Signaling. 2014;20(5):783-793.

    Not in our library10.1089/ars.2013.5309

31. 31.

    Benavides G. A., Squadrito G. L., Mills R. W., et al. Hydrogen sulfide mediates the vasoactivity of garlic. Proceedings of the National Academy of Sciences of the United States of America. 2007;104(46):17977-17982.

    Not in our library10.1073/pnas.0705710104

32. 32.

    Predmore B. L., Kondo K., Bhushan S., et al. The polysulfide diallyl trisulfide protects the ischemic myocardium by preservation of endogenous hydrogen sulfide and increasing nitric oxide bioavailability. American Journal of Physiology—Heart and Circulatory Physiology. 2012;302(11):H2410-H2418.

    Not in our library10.1152/ajpheart.00044.2012

33. 33.

    Snijder P. M., Frenay A. S., de Boer R. A., et al. Exogenous administration of thiosulfate, a donor of hydrogen sulfide, attenuates Angiotensin II-induced hypertensive heart disease in rats. British Journal of Pharmacology. 2014.

    Not in our library10.1111/bph.12825

34. 34.

    Imai T., Kosuge Y., Endo-Umeda K., et al. Protective effect of S-allyl-l-cysteine against endoplasmic reticulum stress-induced neuronal death is mediated by inhibition of calpain. Amino Acids. 2014;46(2):385-393.

    Not in our library10.1007/s00726-013-1628-4

35. 35.

    Zhao Y., Biggs T. D., Xian M. Hydrogen sulfide (H2S) releasing agents: chemistry and biological applications. Chemical Communications (Cambridge). 2014;50(80):11788-11805.

    Not in our library10.1039/c4cc00968a

36. 36.

    Snijder P. M., de Boer R. A., Bos E. M., et al. Gaseous hydrogen sulfide protects against myocardial ischemia-reperfusion injury in mice partially independent from hypometabolism. PLoS ONE. 2013;8(5).

    Not in our library10.1371/journal.pone.0063291

37. 37.

    Kabil O., Banerjee R. Redox biochemistry of hydrogen sulfide. The Journal of Biological Chemistry. 2010;285(29):21903-21907.

    Not in our library10.1074/jbc.r110.128363

38. 38.

    Hildebrandt T. M., Grieshaber M. K. Three enzymatic activities catalyze the oxidation of sulfide to thiosulfate in mammalian and invertebrate mitochondria. FEBS Journal. 2008;275(13):3352-3361.

    Not in our library10.1111/j.1742-4658.2008.06482.x

39. 39.

    Lee G.-J., Kim S. K., Kang S. W., et al. Real time measurement of myocardial oxygen dynamics during cardiac ischemia-reperfusion of rats. Analyst. 2012;137(22):5312-5319.

    Not in our library10.1039/c2an35208g

40. 40.

    Fauconnier J., Meli A. C., Thireau J., et al. Ryanodine receptor leak mediated by caspase-8 activation leads to left ventricular injury after myocardial ischemia-reperfusion. Proceedings of the National Academy of Sciences of the United States of America. 2011;108(32):13258-13263.

    Not in our library10.1073/pnas.1100286108

Cited by papers we hold 2

• Rapid and selective generation of H2S within mitochondria protects against cardiac ischemia-reperfusion injury · 2022
  Not checked
• Hydrogen Sulfide in Physiology and Diseases of the Digestive Tract · 2015
  No notice

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