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Characterization of the Blood and Cerebrospinal Fluid Microbiome in Children with Bacterial Meningitis and Its Potential Correlation with Inflammation

Huiping Liao, Yuchao Zhang, Wei Guo and 11 more

mSystems · 2021

doi:10.1128/msystems.00049-21 (opens in a new tab)

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Abstract

This study revealed the microbial compositions in children with bacterial meningitis who were treated with antibiotics and made a comprehensive comparison between blood and CSF specimens for risk and prognosis assessment. We found that microbiome signatures could distinguish patient subsets and were correlated with the CRP level in blood and granulocyte percentage in CSF.

Abstract licence: CC BY

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