Acceleration of oligomerization, not fibrillization, is a shared property of both α-synuclein mutations linked to early-onset Parkinson's disease: Implications for pathogenesis and therapy

Cited by papers we hold 31

• Pathological structural conversion of α-synuclein at the mitochondria induces neuronal toxicity · 2022
  Corrected
• A multi-step nucleation process determines the kinetics of prion-like domain phase separation · 2021
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• The structural differences between patient-derived α-synuclein strains dictate characteristics of Parkinson’s disease, multiple system atrophy and dementia with Lewy bodies · 2020
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• Alpha-Synuclein Physiology and Pathology: A Perspective on Cellular Structures and Organelles · 2020
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• Microglia as modulators of exosomal alpha-synuclein transmission · 2019
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• Amyloid assembly and disassembly · 2018
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• Mechanisms of α-Synuclein Induced Synaptopathy in Parkinson's Disease · 2018
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• Alpha-Synuclein: From Early Synaptic Dysfunction to Neurodegeneration · 2018
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• Cardiolipin exposure on the outer mitochondrial membrane modulates α-synuclein · 2018
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• microRNAs in Parkinson’s Disease: From Pathogenesis to Novel Diagnostic and Therapeutic Approaches · 2017
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• Structural and functional properties of prefibrillar α-synuclein oligomers · 2016
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• Alpha-Synuclein Oligomers—Neurotoxic Molecules in Parkinson's Disease and Other Lewy Body Disorders · 2016
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• Alpha-Synuclein in Parkinson’s Disease: From Pathogenetic Dysfunction to Potential Clinical Application · 2016
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• Propagation of alpha-synuclein pathology: hypotheses, discoveries, and yet unresolved questions from experimental and human brain studies · 2015
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• Seeking a Mechanism for the Toxicity of Oligomeric α-Synuclein · 2015
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• Systematic Comparison of the Effects of Alpha-synuclein Mutations on Its Oligomerization and Aggregation · 2014
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• Use of Caenorhabditis elegans as a model to study Alzheimer’s disease and other neurodegenerative diseases · 2014
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• Shared Mechanisms of Neurodegeneration in Alzheimer’s Disease and Parkinson’s Disease · 2014
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• Targeting the Intrinsically Disordered Structural Ensemble of α-Synuclein by Small Molecules as a Potential Therapeutic Strategy for Parkinson’s Disease · 2014
  Corrected
• Transfer of human α-synuclein from the olfactory bulb to interconnected brain regions in mice · 2013
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and 11 more

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