Dynamic prioritization of COVID-19 vaccines when social distancing is limited for essential workers

Abstract

Significance Vaccines are a key intervention to reduce the burden of the COVID-19 pandemic. However, vaccine supply and administration capacity will initially be limited. Due to these constraints, it is critical to understand how vaccine deployment can be targeted to minimize the overall burden of disease. In this paper, we solve for optimal dynamic strategies to allocate a limited supply of vaccines over a population differentiated by age and essential worker status that minimizes the number of total deaths, years of life lost, or infections. We find that older essential workers are typically targeted first. However, depending on the objective and alternative model scenarios considered, younger essential workers may be prioritized to control spread or seniors to directly control mortality.

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Cited by papers we hold 4

• Optimal spatial evaluation of a pro rata vaccine distribution rule for COVID-19 · 2023
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• Novel dynamic fuzzy Decision-Making framework for COVID-19 vaccine dose recipients · 2022
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• Models of COVID-19 vaccine prioritisation: a systematic literature search and narrative review · 2021
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• Model-informed COVID-19 vaccine prioritization strategies by age and serostatus · 2021
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