Lipoic acid functions in Paneth cells to prevent human intestinal stem cell aging
Zehong Zhang, Qianyi Wan, Yuedan Zhu et al. · Nature Communications · 2025
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Aging
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41 papersQuestions on this topic
Spatiotemporal profiling reveals the impact of caloric restriction in the aging mammalian brain
Zehao Zhang, Alexander Epstein, Chloe Schaefer et al. · Cell Reports · 2025
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Intrinsic cardiorespiratory fitness modulates clinical and molecular response to caloric restriction
Johanna Y. Fleischman, Nathan R. Qi, Mary K. Treutelaar et al. · Molecular Metabolism · 2023
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Markers of aging: Unsupervised integrated analyses of the human plasma proteome
L. Coenen, L. Coenen, B. Lehallier et al. · Frontiers in Aging · 2023
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Metabolic benefits of methionine restriction in adult mice do not require functional methionine sulfoxide reductase A (MsrA)
Kevin M. Thyne, Adam B. Salmon · Scientific Reports · 2022
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Genetic variation in ALDH4A1 is associated with muscle health over the lifespan and across species
Osvaldo Villa, Nicole L Stuhr, Chia-an Yen et al. · eLife · 2022
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Intestinal stem cell aging signature reveals a reprogramming strategy to enhance regenerative potential
Christian M. Nefzger, Thierry Jardé, Akanksha Srivastava et al. · npj Regenerative Medicine · 2022
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Geroprotectors and Skeletal Health: Beyond the Headlines
Alexandra Rayson, Maya Boudiffa, Maneeha Naveed et al. · Frontiers in Cell and Developmental Biology · 2022
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Extract from the stem of Tinospora crispa (L.) Hook. f. & Thomson extends life span and decreases stress-induced mortality in Drosophila melanogaster
Nattapong Wongchum, Ananya Dechakhamphu · Pharmaceutical Sciences Asia · 2022
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Dicer1 deficient mice exhibit premature aging and metabolic perturbations in adipocytes
Aurore De Cauwer, Thomas Loustau, William Erne et al. · iScience · 2022
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Potential Roles of PTEN on Longevity in Two Closely Related Argopecten Scallops With Distinct Lifespans
Hanzhi Xu, Xia Lu, Chunde Wang et al. · Frontiers in Physiology · 2022
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A Comprehensive Overview of the Complex Role of Oxidative Stress in Aging, The Contributing Environmental Stressors and Emerging Antioxidant Therapeutic Interventions
Evripides Iakovou, Malamati Kourti, Malamati Kourti · Frontiers in Aging Neuroscience · 2022
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A sphingolipid-mTORC1 nutrient-sensing pathway regulates animal development by an intestinal peroxisome relocation-based gut-brain crosstalk
Na Li, Beilei Hua, Qing Chen et al. · Cell Reports · 2022
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A new era for research into aging
Matt Kaeberlein, Jessica K Tyler · eLife · 2021
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The biphasic and age-dependent impact of klotho on hallmarks of aging and skeletal muscle function
Zachary Clemens, Sruthi Sivakumar, Abish Pius et al. · eLife · 2021
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Liquid-culture protocols for synchronous starvation, growth, dauer formation, and dietary restriction of Caenorhabditis elegans
Jonathan D. Hibshman, Amy K. Webster, L. Ryan Baugh · STAR Protocols · 2021
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The Accumulating Costs Hypothesis—to Better Understand Delayed “Hidden” Costs of Seemingly Mild Disease and Other Moderate Stressors
Dennis Hasselquist, Michael Tobler · Frontiers in Ecology and Evolution · 2021
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Loss of Mir146b with aging contributes to inflammation and mitochondrial dysfunction in thioglycollate-elicited peritoneal macrophages
Andrea Santeford, Aaron Y Lee, Abdoulaye Sene et al. · eLife · 2021
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Diverse biological processes coordinate the transcriptional response to nutritional changes in a Drosophila melanogaster multiparent population
E. Ng’oma, P. A. Williams-Simon, A. Rahman et al. · BMC Genomics · 2020
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Polyunsaturated fatty acids and p38-MAPK link metabolic reprogramming to cytoprotective gene expression during dietary restriction
Manish Chamoli, Anita Goyala, Syed Shamsh Tabrez et al. · Nature Communications · 2020
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