A small-molecule TNIK inhibitor targets fibrosis in preclinical and clinical models
Feng Ren, Alex Aliper, Jian Chen et al. · Nature Biotechnology · 2024 · Randomised trial
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Pulmonary and Respiratory Medicine
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Outcomes of Observation vs Stereotactic Ablative Radiation for Oligometastatic Prostate Cancer
Ryan Phillips, William Yue Shi, Matthew Deek et al. · JAMA Oncology · 2020 · Randomised trial
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Survival and prognosis with osteosarcoma: outcomes in more than 2000 patients in the EURAMOS-1 (European and American Osteosarcoma Study) cohort
Sigbjørn Smeland, Stefan S. Bielack, Jeremy Whelan et al. · European Journal of Cancer · 2019 · Randomised trial
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Restenosis and risk of stroke after stenting or endarterectomy for symptomatic carotid stenosis in the International Carotid Stenting Study (ICSS): secondary analysis of a randomised trial
Leo H Bonati, John Gregson, Joanna Dobson et al. · The Lancet Neurology · 2018 · Randomised trial
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Early circulating tumor DNA dynamics and clonal selection with palbociclib and fulvestrant for breast cancer
Ben O’Leary, Sarah Hrebien, James P. Morden et al. · Nature Communications · 2018 · Randomised trial
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Efficacy and safety of palbociclib in combination with letrozole as first-line treatment of ER-positive, HER2-negative, advanced breast cancer: expanded analyses of subgroups from the randomized pivotal trial PALOMA-1/TRIO-18
Richard S. Finn, John P. Crown, Johannes Ettl et al. · Breast Cancer Research · 2016 · Randomised trial
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Heterogeneity and clinical significance of ESR1 mutations in ER-positive metastatic breast cancer patients receiving fulvestrant
Jill M. Spoerke, Steven Gendreau, Kimberly Walter et al. · Nature Communications · 2016 · Randomised trial
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Effect of driving pressure on mortality in ARDS patients during lung protective mechanical ventilation in two randomized controlled trials
on behalf of the investigators of the Acurasys and Proseva trials, Claude Guérin, Laurent Papazian et al. · Critical Care · 2016 · Randomised trial
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Addition of docetaxel, zoledronic acid, or both to first-line long-term hormone therapy in prostate cancer (STAMPEDE): survival results from an adaptive, multiarm, multistage, platform randomised controlled trial
Nicholas D James, Matthew R Sydes, Noel W Clarke et al. · The Lancet · 2016 · Randomised trial
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TOPGEAR: a randomised phase III trial of perioperative ECF chemotherapy versus preoperative chemoradiation plus perioperative ECF chemotherapy for resectable gastric cancer (an international, intergroup trial of the AGITG/TROG/EORTC/NCIC CTG)
Trevor Leong, B Mark Smithers, Michael Michael et al. · BMC Cancer · 2015 · Randomised trial
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Fulvestrant 500 mg Versus Anastrozole 1 mg for the First-Line Treatment of Advanced Breast Cancer: Overall Survival Analysis From the Phase II FIRST Study
Matthew J. Ellis, Antonio Llombart-Cussac, David Feltl et al. · Journal of Clinical Oncology · 2015 · Randomised trial
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HER2 screening data from ToGA: targeting HER2 in gastric and gastroesophageal junction cancer
Eric Van Cutsem, Yung-Jue Bang, Feng Feng-yi et al. · Gastric Cancer · 2014 · Randomised trial
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First-line erlotinib in patients with advanced non-small-cell lung cancer unsuitable for chemotherapy (TOPICAL): a double-blind, placebo-controlled, phase 3 trial
Siow Ming Lee, Iftekhar Khan, Sunil Upadhyay et al. · The Lancet Oncology · 2012 · Randomised trial
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Neo-adjuvant chemotherapy followed by surgery and chemotherapy or by surgery and chemoradiotherapy for patients with resectable gastric cancer (CRITICS)
Johan L Dikken, Johanna W van Sandick, HA Maurits Swellengrebel et al. · BMC Cancer · 2011 · Randomised trial
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A panel of kallikrein markers can reduce unnecessary biopsy for prostate cancer: data from the European Randomized Study of Prostate Cancer Screening in Göteborg, Sweden
Andrew J Vickers, Angel M Cronin, Gunnar Aus et al. · BMC Medicine · 2008 · Randomised trial
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Long-term survival after epirubicin, cisplatin and fluorouracil for gastric cancer: results of a randomized trial
J S Waters, A Norman, D Cunningham et al. · British Journal of Cancer · 1999 · Randomised trial
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