Triple hormone receptor agonist retatrutide for metabolic dysfunction-associated steatotic liver disease: a randomized phase 2a trial
Arun J. Sanyal, Lee M. Kaplan, Juan P. Frias et al. · Nature Medicine · 2024 · Randomised trial
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Long-term weight loss effects of semaglutide in obesity without diabetes in the SELECT trial
Donna H. Ryan, Ildiko Lingvay, John Deanfield et al. · Nature Medicine · 2024 · Randomised trial
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A small-molecule TNIK inhibitor targets fibrosis in preclinical and clinical models
Feng Ren, Alex Aliper, Jian Chen et al. · Nature Biotechnology · 2024 · Randomised trial
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Blinded, randomized trial of sonographer versus AI cardiac function assessment
Bryan He, Alan C. Kwan, Jae Hyung Cho et al. · Nature · 2023 · Randomised trial
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Preoperative Chemotherapy for Operable Colon Cancer: Mature Results of an International Randomized Controlled Trial
Dion Morton, Matthew Seymour, Laura Magill et al. · Journal of Clinical Oncology · 2023 · Randomised trial
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Toripalimab combined with lenvatinib and GEMOX is a promising regimen as first-line treatment for advanced intrahepatic cholangiocarcinoma: a single-center, single-arm, phase 2 study
Guo-Ming Shi, Xiao-Yong Huang, Dong Wu et al. · Signal Transduction and Targeted Therapy · 2023 · Randomised trial
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Effect of Electroacupuncture on Insomnia in Patients With Depression
Xuan Yin, Wei Li, Tingting Liang et al. · JAMA Network Open · 2022 · Randomised trial
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Effect of Artificial Intelligence Tutoring vs Expert Instruction on Learning Simulated Surgical Skills Among Medical Students
Ali M. Fazlollahi, Mohamad Bakhaidar, Ahmad Alsayegh et al. · JAMA Network Open · 2022 · Randomised trial
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Cardiovascular outcomes in adults with hypertension with evening versus morning dosing of usual antihypertensives in the UK (TIME study): a prospective, randomised, open-label, blinded-endpoint clinical trial
Isla S Mackenzie, Amy Rogers, Neil R Poulter et al. · The Lancet · 2022 · Randomised trial
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Two-year effects of semaglutide in adults with overweight or obesity: the STEP 5 trial
W. Timothy Garvey, Rachel L. Batterham, Meena Bhatta et al. · Nature Medicine · 2022 · Randomised trial
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Mindfulness-Oriented Recovery Enhancement vs Supportive Group Therapy for Co-occurring Opioid Misuse and Chronic Pain in Primary Care
Eric L. Garland, Adam W. Hanley, Yoshio Nakamura et al. · JAMA Internal Medicine · 2022 · Randomised trial
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Daratumumab plus lenalidomide and dexamethasone in transplant-ineligible newly diagnosed multiple myeloma: frailty subgroup analysis of MAIA
Thierry Facon, Gordon Cook, Saad Z. Usmani et al. · Leukemia · 2022 · Randomised trial
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The efficacy and safety of β-nicotinamide mononucleotide (NMN) supplementation in healthy middle-aged adults: a randomized, multicenter, double-blind, placebo-controlled, parallel-group, dose-dependent clinical trial
Lin Yi, Andrea B. Maier, Rongsheng Tao et al. · GeroScience · 2022 · Randomised trial
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Comparison of SARS-CoV-2 Antibody Response 4 Weeks After Homologous vs Heterologous Third Vaccine Dose in Kidney Transplant Recipients
Roman Reindl-Schwaighofer, Andreas Heinzel, Manuel Mayrdorfer et al. · JAMA Internal Medicine · 2022 · Randomised trial
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Randomized phase III study of gemcitabine, cisplatin plus S‐1 versus gemcitabine, cisplatin for advanced biliary tract cancer ( KHBO1401 ‐ MITSUBA )
Tatsuya Ioka, Masashi Kanai, Shogo Kobayashi et al. · Journal of Hepato-Biliary-Pancreatic Sciences · 2022 · Randomised trial
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Sotigalimab and/or nivolumab with chemotherapy in first-line metastatic pancreatic cancer: clinical and immunologic analyses from the randomized phase 2 PRINCE trial
Lacey J. Padrón, Deena M. Maurer, Mark H. O’Hara et al. · Nature Medicine · 2022 · Randomised trial
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Spectacle Lenses With Aspherical Lenslets for Myopia Control vs Single-Vision Spectacle Lenses
Jinhua Bao, Yingying Huang, Xue Li et al. · JAMA Ophthalmology · 2022 · Randomised trial
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Efficacy of Single-Dose Human Papillomavirus Vaccination among Young African Women
Ruanne V. Barnabas, Elizabeth R. Brown, Maricianah A. Onono et al. · NEJM Evidence · 2022 · Randomised trial
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A Therapeutic Relational Agent for Reducing Problematic Substance Use (Woebot): Development and Usability Study
Judith J Prochaska, Erin A Vogel, Amy Chieng et al. · Journal of Medical Internet Research · 2021 · Randomised trial
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Side Effect Patterns in a Crossover Trial of Statin, Placebo, and No Treatment
James P. Howard, Frances A. Wood, Judith A. Finegold et al. · Journal of the American College of Cardiology · 2021 · Randomised trial
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