The Importance of Animal Models in Biomedical Research: Current Insights and Applications
Adriana Domínguez-Oliva, Ismael Hernández-Ávalos, Julio Martínez-Burnes et al. · Animals · 2023 · Review
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31 papersQuestions on this topic
New approach methodologies in human regulatory toxicology – Not if, but how and when!
Sebastian Schmeisser, Andrea Miccoli, Martin von Bergen et al. · Environment International · 2023 · Review
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Role of animal models in biomedical research: a review
P. Mukherjee, S. Roy, D. Ghosh et al. · Laboratory Animal Research · 2022 · Review
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In silico trials: Verification, validation and uncertainty quantification of predictive models used in the regulatory evaluation of biomedical products
Marco Viceconti, Francesco Pappalardo, Blanca Rodriguez et al. · Methods · 2021
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Bovine brucellosis – a comprehensive review
Sandip Kumar Khurana, Anju Sehrawat, Ruchi Tiwari et al. · Veterinary Quarterly · 2021 · Review
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Genomic and transcriptomic variation defines the chromosome-scale assembly of Haemonchus contortus, a model gastrointestinal worm
Stephen R. Doyle, Alan Tracey, Roz Laing et al. · Communications Biology · 2020
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Optimization of cell viability assays to improve replicability and reproducibility of cancer drug sensitivity screens
Peter Larsson, Hanna Engqvist, Jana Biermann et al. · Scientific Reports · 2020
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Building and Applying Quantitative Adverse Outcome Pathway Models for Chemical Hazard and Risk Assessment
Edward J. Perkins, Roman Ashauer, Lyle Burgoon et al. · Environmental Toxicology and Chemistry · 2019 · Review
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Animal to human translation: a systematic scoping review of reported concordance rates
Cathalijn H. C. Leenaars, Carien Kouwenaar, Frans R. Stafleu et al. · Journal of Translational Medicine · 2019 · Review
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Prevalence, duration and risk factors for appendicular osteoarthritis in a UK dog population under primary veterinary care
Katharine L. Anderson, Dan G. O’Neill, David C. Brodbelt et al. · Scientific Reports · 2018
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ARRIVE has not ARRIVEd: Support for the ARRIVE (Animal Research: Reporting of in vivo Experiments) guidelines does not improve the reporting quality of papers in animal welfare, analgesia or anesthesia
Vivian Leung, Frédérik Rousseau-Blass, Guy Beauchamp et al. · PLOS ONE · 2018
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Recovering The Principles of Humane Experimental Technique
Robert G. W. Kirk · Science, Technology, & Human Values · 2017
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Pain and Laboratory Animals: Publication Practices for Better Data Reproducibility and Better Animal Welfare
Larry Carbone, Jamie Austin · PLOS ONE · 2016
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Updating Animal Welfare Thinking: Moving beyond the “Five Freedoms” towards “A Life Worth Living”
David Mellor · Animals · 2016
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Refinement of intraperitoneal injection of sodium pentobarbital for euthanasia in laboratory rats (Rattus norvegicus)
Katie K Zatroch, Cameron G. Knight, Julie N. Reimer et al. · BMC Veterinary Research · 2016
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Recent advances in Brucella abortus vaccines
Elaine MS Dorneles, Nammalwar Sriranganathan, Andrey P. Lage · Veterinary Research · 2015 · Review
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Limitations of the 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl-2H-tetrazolium bromide (MTT) assay when compared to three commonly used cell enumeration assays
Alet van Tonder, Annie M Joubert, A Duncan Cromarty · BMC Research Notes · 2015
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Distinguishing between Exploratory and Confirmatory Preclinical Research Will Improve Translation
Jonathan Kimmelman, Jeffrey S. Mogil, Ulrich Dirnagl · PLoS Biology · 2014
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Progress in Using Systematic Reviews of Animal Studies to Improve Translational Research
C. R. Hooijmans, M. Ritskes-Hoitinga · PLoS Medicine · 2013
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New developments in the evolution and application of the WHO/IPCS framework on mode of action/species concordance analysis
M. E. Meek, A. Boobis, I. Cote et al. · Journal of Applied Toxicology · 2013 · Review
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