Once-Weekly Semaglutide in Adults With Alcohol Use Disorder
Christian S. Hendershot, Michael P. Bremmer, Michael B. Paladino et al. · JAMA Psychiatry · 2025 · Randomised trial
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1,493 papers1 Expression of concern94 Corrected
Efficacy and Safety of Baxdrostat in Uncontrolled and Resistant Hypertension
John M. Flack, Michel Azizi, Jenifer M. Brown et al. · New England Journal of Medicine · 2025 · Randomised trial
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Towards conversational diagnostic artificial intelligence
Tao Tu, Mike Schaekermann, Anil Palepu et al. · Nature · 2025 · Randomised trial
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Pembrolizumab and chemotherapy in high-risk, early-stage, ER+/HER2− breast cancer: a randomized phase 3 trial
Fatima Cardoso, Joyce O’Shaughnessy, Zhenzhen Liu et al. · Nature Medicine · 2025 · Randomised trial
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Neoadjuvant nivolumab and chemotherapy in early estrogen receptor-positive breast cancer: a randomized phase 3 trial
Sherene Loi, Roberto Salgado, Giuseppe Curigliano et al. · Nature Medicine · 2025 · Randomised trial
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Individual and additive effects of vitamin D, omega-3 and exercise on DNA methylation clocks of biological aging in older adults from the DO-HEALTH trial
Heike A. Bischoff-Ferrari, Stephanie Gängler, Maud Wieczorek et al. · Nature Aging · 2025 · Randomised trial
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Corrected A biomarker-stratified comparison of top-down versus accelerated step-up treatment strategies for patients with newly diagnosed Crohn's disease (PROFILE): a multicentre, open-label randomised controlled trial
Nurulamin M Noor, James C Lee, Simon Bond et al. · The Lancet Gastroenterology & Hepatology · 2024 · Randomised trial
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Corrected Updated safety results from phase 3 lecanemab study in early Alzheimer’s disease
Lawrence S. Honig, Marwan N. Sabbagh, Christopher H. van Dyck et al. · Alzheimer's Research & Therapy · 2024 · Randomised trial
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Organ Preservation and Survival by Clinical Response Grade in Patients With Rectal Cancer Treated With Total Neoadjuvant Therapy
Hannah M. Thompson, Dana M. Omer, Sabrina Lin et al. · JAMA Network Open · 2024 · Randomised trial
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Efficacy and Safety of Respiratory Syncytial Virus (RSV) Prefusion F Protein Vaccine (RSVPreF3 OA) in Older Adults Over 2 RSV Seasons
Michael G Ison, Alberto Papi, Eugene Athan et al. · Clinical Infectious Diseases · 2024 · Randomised trial
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Benmelstobart, anlotinib and chemotherapy in extensive-stage small-cell lung cancer: a randomized phase 3 trial
Ying Cheng, Jianhua Chen, Wei Zhang et al. · Nature Medicine · 2024 · Randomised trial
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Dual-energy lattice-tip ablation system for persistent atrial fibrillation: a randomized trial
Elad Anter, Moussa Mansour, Devi G. Nair et al. · Nature Medicine · 2024 · Randomised trial
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Extended pleurectomy decortication and chemotherapy versus chemotherapy alone for pleural mesothelioma (MARS 2): a phase 3 randomised controlled trial
Eric Lim, David Waller, Kelvin Lau et al. · The Lancet Respiratory Medicine · 2024 · Randomised trial
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Bone Health After Exercise Alone, GLP-1 Receptor Agonist Treatment, or Combination Treatment
Simon Birk Kjær Jensen, Victor Sørensen, Rasmus Michael Sandsdal et al. · JAMA Network Open · 2024 · Randomised trial
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Transcatheter or surgical aortic valve implantation: 10-year outcomes of the NOTION trial
Hans Gustav Hørsted Thyregod, Troels Højsgaard Jørgensen, Nikolaj Ihlemann et al. · European Heart Journal · 2024 · Randomised trial
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Long-term kidney outcomes of semaglutide in obesity and cardiovascular disease in the SELECT trial
Helen M. Colhoun, Ildiko Lingvay, Paul M. Brown et al. · Nature Medicine · 2024 · Randomised trial
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Trastuzumab deruxtecan versus trastuzumab emtansine in HER2-positive metastatic breast cancer: long-term survival analysis of the DESTINY-Breast03 trial
Javier Cortés, Sara A. Hurvitz, Seock-Ah Im et al. · Nature Medicine · 2024 · Randomised trial
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AI-Generated Draft Replies Integrated Into Health Records and Physicians’ Electronic Communication
Ming Tai-Seale, Sally L. Baxter, Florin Vaida et al. · JAMA Network Open · 2024 · Randomised trial
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A GIPR antagonist conjugated to GLP-1 analogues promotes weight loss with improved metabolic parameters in preclinical and phase 1 settings
Murielle M. Véniant, Shu-Chen Lu, Larissa Atangan et al. · Nature Metabolism · 2024 · Randomised trial
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Effects of a personalized nutrition program on cardiometabolic health: a randomized controlled trial
Kate M. Bermingham, Inbar Linenberg, Lorenzo Polidori et al. · Nature Medicine · 2024 · Randomised trial
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