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Amyloid and Tau Prediction of Cognitive and Functional Decline in Unimpaired Older Individuals: Longitudinal Data from the A4 and LEARN Studies
Reisa A. Sperling, M.C. Donohue, R.A. Rissman et al. · The Journal of Prevention of Alzheimer's Disease · 2024 · Randomised trial
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Neoadjuvant chemotherapy with or without camrelizumab in resectable esophageal squamous cell carcinoma: the randomized phase 3 ESCORT-NEO/NCCES01 trial
Jianjun Qin, Liyan Xue, Anlin Hao et al. · Nature Medicine · 2024 · Randomised trial
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Resistant starch intake facilitates weight loss in humans by reshaping the gut microbiota
Huating Li, Lei Zhang, Jun Li et al. · Nature Metabolism · 2024 · Randomised trial
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Effects of tirzepatide on circulatory overload and end-organ damage in heart failure with preserved ejection fraction and obesity: a secondary analysis of the SUMMIT trial
Barry A. Borlaug, Michael R. Zile, Christopher M. Kramer et al. · Nature Medicine · 2024 · Randomised trial
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Effects of semaglutide with and without concomitant SGLT2 inhibitor use in participants with type 2 diabetes and chronic kidney disease in the FLOW trial
Johannes F. E. Mann, Peter Rossing, George Bakris et al. · Nature Medicine · 2024 · Randomised trial
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Triple hormone receptor agonist retatrutide for metabolic dysfunction-associated steatotic liver disease: a randomized phase 2a trial
Arun J. Sanyal, Lee M. Kaplan, Juan P. Frias et al. · Nature Medicine · 2024 · Randomised trial
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Long-term weight loss effects of semaglutide in obesity without diabetes in the SELECT trial
Donna H. Ryan, Ildiko Lingvay, John Deanfield et al. · Nature Medicine · 2024 · Randomised trial
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A small-molecule TNIK inhibitor targets fibrosis in preclinical and clinical models
Feng Ren, Alex Aliper, Jian Chen et al. · Nature Biotechnology · 2024 · Randomised trial
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Blinded, randomized trial of sonographer versus AI cardiac function assessment
Bryan He, Alan C. Kwan, Jae Hyung Cho et al. · Nature · 2023 · Randomised trial
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Asciminib vs bosutinib in chronic-phase chronic myeloid leukemia previously treated with at least two tyrosine kinase inhibitors: longer-term follow-up of ASCEMBL
Andreas Hochhaus, Delphine Réa, Carla Boquimpani et al. · Leukemia · 2023 · Randomised trial
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Natriuresis-guided diuretic therapy in acute heart failure: a pragmatic randomized trial
Jozine M. ter Maaten, Iris E. Beldhuis, Peter van der Meer et al. · Nature Medicine · 2023 · Randomised trial
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ctDNA response after pembrolizumab in non-small cell lung cancer: phase 2 adaptive trial results
Valsamo Anagnostou, Cheryl Ho, Garth Nicholas et al. · Nature Medicine · 2023 · Randomised trial
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Effectiveness of Lumbar Cerebrospinal Fluid Drain Among Patients With Aneurysmal Subarachnoid Hemorrhage
Stefan Wolf, Dorothee Mielke, Christoph Barner et al. · JAMA Neurology · 2023 · Randomised trial
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Evinacumab in severe hypertriglyceridemia with or without lipoprotein lipase pathway mutations: a phase 2 randomized trial
Robert S. Rosenson, Daniel Gaudet, Christie M. Ballantyne et al. · Nature Medicine · 2023 · Randomised trial
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Estimation of cell lineages in tumors from spatial transcriptomics data
Beibei Ru, Jinlin Huang, Yu Zhang et al. · Nature Communications · 2023 · Randomised trial
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Trofinetide for the treatment of Rett syndrome: a randomized phase 3 study
Jeffrey L. Neul, Alan K. Percy, Timothy A. Benke et al. · Nature Medicine · 2023 · Randomised trial
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A Placebo-Controlled Trial of Percutaneous Coronary Intervention for Stable Angina
Christopher A. Rajkumar, Michael J. Foley, Fiyyaz Ahmed-Jushuf et al. · New England Journal of Medicine · 2023 · Randomised trial
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Resmetirom for nonalcoholic fatty liver disease: a randomized, double-blind, placebo-controlled phase 3 trial
Stephen A. Harrison, Rebecca Taub, Guy W. Neff et al. · Nature Medicine · 2023 · Randomised trial
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Dupilumab in patients with prurigo nodularis: two randomized, double-blind, placebo-controlled phase 3 trials
Gil Yosipovitch, Nicholas Mollanazar, Sonja Ständer et al. · Nature Medicine · 2023 · Randomised trial
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Normothermic machine perfusion versus static cold storage in donation after circulatory death kidney transplantation: a randomized controlled trial
Sarah A. Hosgood, Christopher J. Callaghan, Colin H. Wilson et al. · Nature Medicine · 2023 · Randomised trial
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