Side Effect Patterns in a Crossover Trial of Statin, Placebo, and No Treatment
James P. Howard, Frances A. Wood, Judith A. Finegold et al. · Journal of the American College of Cardiology · 2021 · Randomised trial
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The comparison effects of intra-articular injection of Platelet Rich Plasma (PRP), Plasma Rich in Growth Factor (PRGF), Hyaluronic Acid (HA), and ozone in knee osteoarthritis; a one year randomized clinical trial
Seyed Ahmad Raeissadat, Parsa Ghazi Hosseini, Mohammad Hasan Bahrami et al. · BMC Musculoskeletal Disorders · 2021 · Randomised trial
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Corrected Convalescent plasma for hospitalized patients with COVID-19: an open-label, randomized controlled trial
Philippe Bégin, Jeannie Callum, Erin Jamula et al. · Nature Medicine · 2021 · Randomised trial
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Comparison of a Single-Session Pain Management Skills Intervention With a Single-Session Health Education Intervention and 8 Sessions of Cognitive Behavioral Therapy in Adults With Chronic Low Back Pain
Beth D. Darnall, Anuradha Roy, Abby L. Chen et al. · JAMA Network Open · 2021 · Randomised trial
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Rituximab versus tocilizumab in anti-TNF inadequate responder patients with rheumatoid arthritis (R4RA): 16-week outcomes of a stratified, biopsy-driven, multicentre, open-label, phase 4 randomised controlled trial
Frances Humby, Patrick Durez, Maya H Buch et al. · The Lancet · 2021 · Randomised trial
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Safety and immunogenicity of SARS-CoV-2 variant mRNA vaccine boosters in healthy adults: an interim analysis
Angela Choi, Matthew Koch, Kai Wu et al. · Nature Medicine · 2021 · Randomised trial
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Colchicine for community-treated patients with COVID-19 (COLCORONA): a phase 3, randomised, double-blinded, adaptive, placebo-controlled, multicentre trial
Jean-Claude Tardif, Nadia Bouabdallaoui, Philippe L L'Allier et al. · The Lancet Respiratory Medicine · 2021 · Randomised trial
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Phase 1 randomized trial of a plant-derived virus-like particle vaccine for COVID-19
Brian J. Ward, Philipe Gobeil, Annie Séguin et al. · Nature Medicine · 2021 · Randomised trial
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Ovarian cancer population screening and mortality after long-term follow-up in the UK Collaborative Trial of Ovarian Cancer Screening (UKCTOCS): a randomised controlled trial
Usha Menon, Aleksandra Gentry-Maharaj, Matthew Burnell et al. · The Lancet · 2021 · Randomised trial
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A multilayer multimodal detection and prediction model based on explainable artificial intelligence for Alzheimer’s disease
Shaker El-Sappagh, Jose M. Alonso, S. M. Riazul Islam et al. · Scientific Reports · 2021 · Randomised trial
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Effect of Empagliflozin on Worsening Heart Failure Events in Patients With Heart Failure and Preserved Ejection Fraction: EMPEROR-Preserved Trial
Milton Packer, Javed Butler, Faiez Zannad et al. · Circulation · 2021 · Randomised trial
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The Effect of Combined Vitamin C and Vitamin E Supplementation on Oxidative Stress Markers in Women with Endometriosis: A Randomized, Triple-Blind Placebo-Controlled Clinical Trial
Leila Amini, Razieh Chekini, Mohammad Reza Nateghi et al. · Pain Research and Management · 2021 · Randomised trial
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Effects of potent neutralizing antibodies from convalescent plasma in patients hospitalized for severe SARS-CoV-2 infection
Arvind Gharbharan, Carlijn C. E. Jordans, Corine GeurtsvanKessel et al. · Nature Communications · 2021 · Randomised trial
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Azithromycin for community treatment of suspected COVID-19 in people at increased risk of an adverse clinical course in the UK (PRINCIPLE): a randomised, controlled, open-label, adaptive platform trial
Christopher C Butler, Jienchi Dorward, Ly-Mee Yu et al. · The Lancet · 2021 · Randomised trial
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Systematic, early rhythm control strategy for atrial fibrillation in patients with or without symptoms: the EAST-AFNET 4 trial
Stephan Willems, Katrin Borof, Axel Brandes et al. · European Heart Journal · 2021 · Randomised trial
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Intravenous methylprednisolone pulse as a treatment for hospitalised severe COVID-19 patients: results from a randomised controlled clinical trial
Maryam Edalatifard, Maryam Akhtari, Mohammadreza Salehi et al. · European Respiratory Journal · 2020 · Randomised trial
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Effect of Vitamin D 3 Supplements on Development of Advanced Cancer
Paulette D. Chandler, Wendy Y. Chen, Oluremi N. Ajala et al. · JAMA Network Open · 2020 · Randomised trial
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A Delayed Morning and Earlier Evening Time-Restricted Feeding Protocol for Improving Glycemic Control and Dietary Adherence in Men with Overweight/Obesity: A Randomized Controlled Trial
Evelyn B. Parr, Brooke L. Devlin, Bridget E. Radford et al. · Nutrients · 2020 · Randomised trial
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Treatment of severe COVID-19 with human umbilical cord mesenchymal stem cells
Lei Shu, Changming Niu, Ruyou Li et al. · Stem Cell Research & Therapy · 2020 · Randomised trial
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Minocycline at 2 Different Dosages vs Placebo for Patients With Mild Alzheimer Disease
Robert Howard, Olga Zubko, Rosie Bradley et al. · JAMA Neurology · 2020 · Randomised trial
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