Cancer Research

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Chronic and Cycling Hypoxia: Drivers of Cancer Chronic Inflammation through HIF-1 and NF-κB Activation: A Review of the Molecular Mechanisms
Jan Korbecki, Donata Simińska, Magdalena Gąssowska-Dobrowolska et al. · International Journal of Molecular Sciences · 2021 · Review
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Role of PFKFB3 and PFKFB4 in Cancer: Genetic Basis, Impact on Disease Development/Progression, and Potential as Therapeutic Targets
Krzysztof Kotowski, Jakub Rosik, Filip Machaj et al. · Cancers · 2021 · Review
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Targeting hypoxic tumor microenvironment in pancreatic cancer
Jinxin Tao, Gang Yang, Wenchuan Zhou et al. · Journal of Hematology & Oncology · 2021 · Review
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MicroRNA Therapeutics in Cancer: Current Advances and Challenges
Soha Reda El Sayed, Justine Cristante, Laurent Guyon et al. · Cancers · 2021 · Review
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HIF-1α/JMJD1A signaling regulates inflammation and oxidative stress following hyperglycemia and hypoxia-induced vascular cell injury
Min Zhao, Shaoting Wang, Anna Zuo et al. · Cellular & Molecular Biology Letters · 2021
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LncRNA H19: A novel oncogene in multiple cancers
Jun Yang, Manlong Qi, Xiang Fei et al. · International Journal of Biological Sciences · 2021 · Review
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Breast Cancer Treatments: Updates and New Challenges
Anna Burguin, Caroline Diorio, Francine Durocher · Journal of Personalized Medicine · 2021 · Review
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Metabolic reprogramming of cancer-associated fibroblasts and its effect on cancer cell reprogramming
Zhenzhen Li, Chanjun Sun, Zhihai Qin · Theranostics · 2021 · Review
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Regulation of the Hypoxia-Inducible Factor (HIF) by Pro-Inflammatory Cytokines
Mykyta I. Malkov, Chee Teik Lee, Cormac T. Taylor · Cells · 2021 · Review
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AMPK–mTOR Signaling and Cellular Adaptations in Hypoxia
Yoomi Chun, Joungmok Kim · International Journal of Molecular Sciences · 2021 · Review
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Tumor microenvironment and radioresistance
Tatsuya Suwa, Minoru Kobayashi, Jin-Min Nam et al. · Experimental & Molecular Medicine · 2021 · Review
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Six distinct NFκB signaling codons convey discrete information to distinguish stimuli and enable appropriate macrophage responses
Adewunmi Adelaja, Brooks Taylor, Katherine M. Sheu et al. · Immunity · 2021
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A novel hypoxic long noncoding RNA KB-1980E6.3 maintains breast cancer stem cell stemness via interacting with IGF2BP1 to facilitate c-Myc mRNA stability
Pengpeng Zhu, Fang He, Yixuan Hou et al. · Oncogene · 2021
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The Mechanism of Warburg Effect-Induced Chemoresistance in Cancer
Chang Liu, Ying Jin, Zhimin Fan · Frontiers in Oncology · 2021 · Review
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Tumor Suppressor miRNA in Cancer Cells and the Tumor Microenvironment: Mechanism of Deregulation and Clinical Implications
Khalid Otmani, Philippe Lewalle · Frontiers in Oncology · 2021 · Review
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SUMOylation controls the binding of hexokinase 2 to mitochondria and protects against prostate cancer tumorigenesis
Xun Shangguan, Jianli He, Zehua Ma et al. · Nature Communications · 2021
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The crosstalk between HIFs and mitochondrial dysfunctions in cancer development
Xingting Bao, Jinhua Zhang, Guomin Huang et al. · Cell Death & Disease · 2021 · Review
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A Narrative Review on Plasminogen Activator Inhibitor-1 and Its (Patho)Physiological Role: To Target or Not to Target?
Machteld Sillen, Paul J. Declerck · International Journal of Molecular Sciences · 2021 · Review
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RNA-induced liquid phase separation of SARS-CoV-2 nucleocapsid protein facilitates NF-κB hyper-activation and inflammation
Yaoxing Wu, Ling Ma, Sihui Cai et al. · Signal Transduction and Targeted Therapy · 2021
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Interaction between CD36 and FABP4 modulates adipocyte-induced fatty acid import and metabolism in breast cancer
Jones Gyamfi, Joo Hye Yeo, Doru Kwon et al. · npj Breast Cancer · 2021
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