Cytosolic DNA sensing by cGAS: regulation, function, and human diseases
Le Yu, Pengda Liu · Signal Transduction and Targeted Therapy · 2021 · Review
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Immunology
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Tissue-specific transcriptional imprinting and heterogeneity in human innate lymphoid cells revealed by full-length single-cell RNA-sequencing
Luca Mazzurana, Paulo Czarnewski, Viktor Jonsson et al. · Cell Research · 2021
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Antigen presentation by lung epithelial cells directs CD4+ TRM cell function and regulates barrier immunity
Anukul T. Shenoy, Carolina Lyon De Ana, Emad I. Arafa et al. · Nature Communications · 2021
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A diamidobenzimidazole STING agonist protects against SARS-CoV-2 infection
Fiachra Humphries, Liraz Shmuel-Galia, Zhaozhao Jiang et al. · Science Immunology · 2021
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Single-cell characterization of macrophages in glioblastoma reveals MARCO as a mesenchymal pro-tumor marker
Andrew X. Chen, Robyn D. Gartrell, Junfei Zhao et al. · Genome Medicine · 2021
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Immunosenescence Study of T Cells: A Systematic Review
Ivon Johanna Rodriguez, Nicolás Lalinde Ruiz, Manuela Llano León et al. · Frontiers in Immunology · 2021 · Systematic review
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B cell-derived GABA elicits IL-10+ macrophages to limit anti-tumour immunity
Baihao Zhang, Alexis Vogelzang, Michio Miyajima et al. · Nature · 2021
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New insights into M1/M2 macrophages: key modulators in cancer progression
Jiuyang Liu, Xiafei Geng, Jinxuan Hou et al. · Cancer Cell International · 2021 · Review
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Manganese salts function as potent adjuvants
Rui Zhang, Chenguang Wang, Yukun Guan et al. · Cellular & Molecular Immunology · 2021
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Macrophage Plasticity and Atherosclerosis Therapy
Ping Lin, Hong-Hai Ji, Yan-Jie Li et al. · Frontiers in Molecular Biosciences · 2021 · Review
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SARS-CoV-2 Membrane Protein Inhibits Type I Interferon Production Through Ubiquitin-Mediated Degradation of TBK1
Liyan Sui, Yinghua Zhao, Wenfang Wang et al. · Frontiers in Immunology · 2021
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Cancer-Associated Fibroblasts and Tumor-Associated Macrophages in Cancer and Cancer Immunotherapy
Hans Raskov, Adile Orhan, Shruti Gaggar et al. · Frontiers in Oncology · 2021 · Review
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Interleukin-7 Biology and Its Effects on Immune Cells: Mediator of Generation, Differentiation, Survival, and Homeostasis
Deng Chen, Ting-Xuan Tang, Hai Deng et al. · Frontiers in Immunology · 2021 · Review
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Current Perspectives on “Off-The-Shelf” Allogeneic NK and CAR-NK Cell Therapies
Erica L. Heipertz, Evan R. Zynda, Tor Espen Stav-Noraas et al. · Frontiers in Immunology · 2021 · Review
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Mitochondrial arginase-2 is essential for IL-10 metabolic reprogramming of inflammatory macrophages
Jennifer K. Dowling, Remsha Afzal, Linden J. Gearing et al. · Nature Communications · 2021
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T cell receptor (TCR) signaling in health and disease
Kinjal Shah, Amr Al-Haidari, Jianmin Sun et al. · Signal Transduction and Targeted Therapy · 2021 · Review
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Low chorionic villous succinate accumulation associates with recurrent spontaneous abortion risk
Xiao-Hui Wang, Sha Xu, Xiang-Yu Zhou et al. · Nature Communications · 2021
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STING enhances cell death through regulation of reactive oxygen species and DNA damage
Thomas J. Hayman, Marta Baro, Tyler MacNeil et al. · Nature Communications · 2021
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A Bittersweet Response to Infection in Diabetes; Targeting Neutrophils to Modify Inflammation and Improve Host Immunity
Rebecca Dowey, Ahmed Iqbal, Simon R. Heller et al. · Frontiers in Immunology · 2021 · Review
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NLRP3 Inflammasome Assembly in Neutrophils Is Supported by PAD4 and Promotes NETosis Under Sterile Conditions
Patrick Münzer, Roberto Negro, Shoichi Fukui et al. · Frontiers in Immunology · 2021
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