The CAFA challenge reports improved protein function prediction and new functional annotations for hundreds of genes through experimental screens
Naihui Zhou, Yuxiang Jiang, Timothy R. Bergquist et al. · Genome Biology · 2019
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Biochemistry, Genetics and Molecular Biology
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pH-responsive and targeted delivery of curcumin via phenylboronic acid-functionalized ZnO nanoparticles for breast cancer therapy
Mousumi Kundu, Pritam Sadhukhan, Noyel Ghosh et al. · Journal of Advanced Research · 2019
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Human Fis1 regulates mitochondrial dynamics through inhibition of the fusion machinery
Rong Yu, Shao‐Bo Jin, Urban Lendahl et al. · The EMBO Journal · 2019
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Organoids as a new model for improving regenerative medicine and cancer personalized therapy in renal diseases
Ludovica Grassi, Romina Alfonsi, Federica Francescangeli et al. · Cell Death & Disease · 2019
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Gut Microbiota Dysbiosis and Increased Plasma LPS and TMAO Levels in Patients With Preeclampsia
Jing Wang, Xunke Gu, Jing Yang et al. · Frontiers in Cellular and Infection Microbiology · 2019
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1,520 reference genomes from cultivated human gut bacteria enable functional microbiome analyses
Yuanqiang Zou, Wenbin Xue, Guangwen Luo et al. · Nature Biotechnology · 2019
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Pathway Commons 2019 Update: integration, analysis and exploration of pathway data
Igor Rodchenkov, Ozgun Babur, Augustin Luna et al. · Nucleic Acids Research · 2019
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Obesity May Accelerate the Aging Process
Valentina Salvestrini, Christian Sell, Antonello Lorenzini · Frontiers in Endocrinology · 2019 · Review
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Alterations in Gut Microbiota by Statin Therapy and Possible Intermediate Effects on Hyperglycemia and Hyperlipidemia
Jiyeon Kim, Heetae Lee, Jinho An et al. · Frontiers in Microbiology · 2019
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Understanding of ROS-Inducing Strategy in Anticancer Therapy
Su Ji Kim, Hyun Soo Kim, Young Rok Seo · Oxidative Medicine and Cellular Longevity · 2019 · Review
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Membrane Lipid Composition: Effect on Membrane and Organelle Structure, Function and Compartmentalization and Therapeutic Avenues
Doralicia Casares, Pablo V. Escribá, Catalina Ana Rosselló · International Journal of Molecular Sciences · 2019 · Review
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Roles of Cyclic AMP Response Element Binding Activation in the ERK1/2 and p38 MAPK Signalling Pathway in Central Nervous System, Cardiovascular System, Osteoclast Differentiation and Mucin and Cytokine Production
Yasuhiko Koga, Hiroaki Tsurumaki, Haruka Aoki-Saito et al. · International Journal of Molecular Sciences · 2019 · Review
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Single particle cryo-EM reconstruction of 52 kDa streptavidin at 3.2 Angstrom resolution
Xiao Fan, Jia Wang, Xing Zhang et al. · Nature Communications · 2019
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Thyroid hormone regulates distinct paths to maturation in pigment cell lineages
Lauren M Saunders, Abhishek K Mishra, Andrew J Aman et al. · eLife · 2019
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Type 1 diabetes defined by severe insulin deficiency occurs after 30 years of age and is commonly treated as type 2 diabetes
Nicholas J. Thomas, Anita L. Lynam, Anita V. Hill et al. · Diabetologia · 2019
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Liquid biopsy in hepatocellular carcinoma: circulating tumor cells and circulating tumor DNA
Qianwei Ye, Sunbin Ling, Shusen Zheng et al. · Molecular Cancer · 2019 · Review
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Exosomes produced from 3D cultures of umbilical cord mesenchymal stem cells in a hollow-fiber bioreactor show improved osteochondral regeneration activity
Litao Yan, Xing Wu · Cell Biology and Toxicology · 2019
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Gut Microbiota-Dependent Marker TMAO in Promoting Cardiovascular Disease: Inflammation Mechanism, Clinical Prognostic, and Potential as a Therapeutic Target
Shengjie Yang, Xinye Li, Fan Yang et al. · Frontiers in Pharmacology · 2019 · Review
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Mesenchymal Stem Cell-Derived Exosomes and Other Extracellular Vesicles as New Remedies in the Therapy of Inflammatory Diseases
Carl Randall Harrell, Nemanja Jovicic, Valentin Djonov et al. · Cells · 2019 · Review
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Fibrillin microfibrils and elastic fibre proteins: Functional interactions and extracellular regulation of growth factors
Jennifer Thomson, Mukti Singh, Alexander Eckersley et al. · Seminars in Cell & Developmental Biology · 2019 · Review
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