AZD7648 is a potent and selective DNA-PK inhibitor that enhances radiation, chemotherapy and olaparib activity
Jacqueline H. L. Fok, Antonio Ramos-Montoya, Mercedes Vazquez-Chantada et al. · Nature Communications · 2019
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Oncology
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Sarcomatoid carcinoma presenting as cancers of unknown primary: a clinicopathological portrait
Ryan W. Huey, Shalini Makawita, Lianchun Xiao et al. · BMC Cancer · 2019
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Editorial: The Role of Chemoattractants in the Tumor Microenvironment
Giovanni Bernardini, Brian A. Zabel · Frontiers in Immunology · 2019
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Oncoviruses Can Drive Cancer by Rewiring Signaling Pathways Through Interface Mimicry
Emine Guven-Maiorov, Chung-Jung Tsai, Ruth Nussinov et al. · Frontiers in Oncology · 2019
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Oncolytic virus immunotherapy induces immunogenic cell death and overcomes STING deficiency in melanoma
Praveen K. Bommareddy, Andrew Zloza, Samuel D. Rabkin et al. · OncoImmunology · 2019
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Endocrine toxicity of immune checkpoint inhibitors: a real-world study leveraging US Food and Drug Administration adverse events reporting system
Yinghong Zhai, Xiaofei Ye, Fangyuan Hu et al. · Journal for ImmunoTherapy of Cancer · 2019
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Characterization of Novel Murine and Human PDAC Cell Models: Identifying the Role of Intestine Specific Homeobox Gene ISX in Hypoxia and Disease Progression
Arsheed A. Ganaie, Aijaz Parray, Tabish Hussain et al. · Translational Oncology · 2019
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Correction to: Selective killing of circulating tumor cells prevents metastasis and extends survival
Yi Rang Kim, Jung Ki Yoo, Chang Wook Jeong et al. · Journal of Hematology & Oncology · 2019
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Comparative analysis of the phase III clinical trials of anti-PD1 monotherapy in head and neck squamous cell carcinoma patients (CheckMate 141 and KEYNOTE 040)
Sara I. Pai, Sandrine Faivre, Lisa Licitra et al. · Journal for ImmunoTherapy of Cancer · 2019
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A Case of Pseudoprogression During Atezolizumab Therapy in Lung Adenocarcinoma
Xue WANG, Yi ZHAO, Zhiwei CHEN · Chinese Journal of Lung Cancer · 2019
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Persistent double strand break accumulation does not precede cell death in an Olaparib-sensitive BRCA-deficient colorectal cancer cell model
Natalia Soledad Paviolo, María Belén de la Vega, María Florencia Pansa et al. · Genetics and Molecular Biology · 2019
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Mechanisms regulating PD-L1 expression on tumor and immune cells
Shuming Chen, George A. Crabill, Theresa S. Pritchard et al. · Journal for ImmunoTherapy of Cancer · 2019
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How we treat metastatic colorectal cancer
Marisol Huerta, Susana Rosello, Fortunato Ciardiello et al. · ESMO Open · 2019
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Safety and efficacy of immune checkpoint inhibitors (ICIs) in cancer patients with HIV, hepatitis B, or hepatitis C viral infection
Neil J. Shah, Ghassan Al-Shbool, Matthew Blackburn et al. · Journal for ImmunoTherapy of Cancer · 2019
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Adjuvant chemotherapy after surgery for pancreatic ductal adenocarcinoma: retrospective real-life data
Sophia Chikhladze, Ann-Kathrin Lederer, Lampros Kousoulas et al. · World Journal of Surgical Oncology · 2019
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Pre-metastatic niche triggers SDF-1/CXCR4 axis and promotes organ colonisation by hepatocellular circulating tumour cells via downregulation of Prrx1
Yujun Tang, Yishi Lu, Yuan Chen et al. · Journal of Experimental & Clinical Cancer Research · 2019
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The Role of Carbon Dioxide Laser Therapy in Penile Kaposi’s Sarcoma: A Case Series of Three HIV-Negative HHV-8-Positive Patients
Tullio Torelli, Biagio Paolini, Mario Achille Catanzaro et al. · Clinical Management Issues · 2019
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Receptor tyrosine kinase-dependent PI3K activation is an escape mechanism to vertical suppression of the EGFR/RAS/MAPK pathway in KRAS-mutated human colorectal cancer cell lines
Pietro Paolo Vitiello, Claudia Cardone, Giulia Martini et al. · Journal of Experimental & Clinical Cancer Research · 2019
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Gain-of-Function Mutant p53: All the Roads Lead to Tumorigenesis
Yan Stein, Varda Rotter, Ronit Aloni-Grinstein · International Journal of Molecular Sciences · 2019 · Review
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Molecular transport through primary human small intestinal monolayers by culture on a collagen scaffold with a gradient of chemical cross-linking
Jennifer E. Speer, Dulan B. Gunasekara, Yuli Wang et al. · Journal of Biological Engineering · 2019
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