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How splicing confers treatment resistance in prostate cancer

Prathyusha Konda, Srinivas R Viswanathan

eLife · 2022

doi:10.7554/elife.82070 (opens in a new tab)

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Abstract

A splice variant of the androgen receptor that drives prostate cancer resistance translocates into the nucleus using a different mechanism from the full-length receptor and exhibits distinct molecular properties once inside.

Abstract licence: CC BY

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