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Reversible Ototoxicity: A Rare Adverse Reaction of Liposomal Amphotericin-B Used for the Treatment of Antimony-Resistant Visceral Leishmaniasis in an Elderly Male

PC Das, Ramesh Kandel, Kapil Sikka and 1 more

Clinical Medicine Insights: Case Reports · 2014

doi:10.4137/ccrep.s15111 (opens in a new tab)

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Abstract

Amphotericin-B, a broad spectrum antifungal agent, has been known to cause adverse effects such as nephrotoxicity and infusion-related side effects such as fever, chills, rigor, and arthralgias. However, ototoxicity as an adverse effect of Amphotericin-B has not yet been reported in medical literature. We here report a case of a reversible form of ototoxicity induced by liposomal Amphotericin-B (L-AmB).

Abstract licence: CC BY-NC

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