Prosthetic valve thrombosis management in a patient with deranged coagulation parameters
Nitin Kumar Parashar, Mumun Sinha, Shanmugam Krishnan and 1 more
Journal of the Practice of Cardiovascular Sciences · 2018
doi:10.4103/jpcs.jpcs_42_18 (opens in a new tab)
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Abstract
Appropriate guidelines are not available at present for the management of patient with acute prosthetic heart valve thrombosis presenting with New York Heart Association Class IV symptoms and having deranged coagulation profile. Here, we thrombolyzed one such patient with tissue plasminogen activator (alteplase) using very slow infusion (25 mg over 24 h) which resulted in rapid improvement in symptoms and subsequent resolution of pulmonary edema with simultaneous improvement of echocardiographic gradient and fluoroscopic movement of leaflets.
Abstract licence: CC BY-NC-SA
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