Diagnostic Dilemmas in Cutaneous Pseudolymphomas

Cutaneous pseudolymphoma (CPL) is an umbrella term encompassing reactive lymphoproliferation that imitates cutaneous lymphomas clinically and/or histopathologically. We present the case of an elderly male presenting with solitary, painless, raised, and progressive swelling on the right side of the face of 9-month duration. Examination revealed a solitary, raised, slightly erythematous nodule without any surface changes. Clinically, the neoplastic differentials were given precedence owing to rapid onset and age at presentation. The nodule was excised in toto and, following histopathological examination and immunohistochemistry (IHC), diagnosed as CPL. We elaborate how pseudolymphomas can mimic lymphoma and can be distinguished only with an integrated clinical, histomorphological approach and the use of ancillary techniques including IHC.

Abstract licence: CC BY-NC-SA

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