A rare case of paediatric non-Hodgkin's lymphoma
D Bhargavi, T Kannan, K L Priyadarshini and 3 more
Journal of Clinical and Scientific Research · 2019
doi:10.4103/jcsr.jcsr_20_18 (opens in a new tab)
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Abstract
Anaplastic large cell lymphoma (ALCL) is a rare disease accounting for 10%–15% of all non-Hodgkin's lymphomas in children. It is distinguished from other lymphomas by their anaplastic cytology and constant membrane expression of the CD30 antigen. We report a 9-year-old boy presented with a left calf swelling. Biopsy from swelling revealed as small cell variant of anaplastic lymphoma kinase-positive ALCL. Staging with positron emission tomography–computed tomography showed lymph nodal and multiple extra-nodal involvement. The extra-nodal sites were lung, pancreas, bone, sphenoid sinus and muscles. He was started on ALCL-99 protocol.
Abstract licence: CC BY-NC-SA
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