Diffuse pleural thickening: cases of pseudomesotheliomatous adenocarcinoma and pleural tuberculosis

Abstract Diffuse pleural thickening is a common cause of diagnostic dilemma. We report two cases of pleural thickening that presented with similar clinical and radiological picture, thus clinching a diagnosis hinged on histopathology. In the first case, the histopatholgy and immunohistochemistry was suggestive of adneocarcinoma, thus making the diagnosis of pseudomesotheliomatous adenocarcinoma. In the second case, the histopathology was suggestive of tubercular etiology, which also is a rare presentation of active pleural tuberculosis. These cases highlight the importance of histopathological examination in establishing the etiology in cases of diffuse pleural thickening.

Abstract licence: CC BY

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