Meta-analysis of risk association between interleukin-17a gene polymorphism and chronic periodontitis
P K Sasikumar, Sheeja S Varghese, Thanga Kumaran and 1 more
Contemporary Clinical Dentistry · 2020
doi:10.4103/ccd.ccd_448_19 (opens in a new tab)
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Abstract
The association of genetic polymorphisms with periodontitis has been studied extensively. The interleukin-7 (IL-17) is a group of cytokines, which comprises six different molecules (IL-17A, B, C, D, E, and F). Among this, IL-17A is the most commonly understood cytokine, and its polymorphism plays a critical role in inflammatory diseases and periodontal inflammation. The present study was aimed at pooling the data available for meta-analysis and to evaluate whether IL-17A (rs2275913) polymorphism is associated with the susceptibility of chronic periodontitis.
Abstract licence: CC BY-NC-SA
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