Hereditary persistence of fetal hemoglobin
Dharmesh Chandra Sharma, Sachin Singhal, Poonam Woike and 3 more
Asian Journal of Transfusion Science · 2020
doi:10.4103/ajts.ajts_71_16 (opens in a new tab)
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Abstract
Hereditary persistence of fetal hemoglobin (HPFH) is a benign condition in which significant fetal hemoglobin production continues well into adulthood, disregarding the normal shutoff point after which only adult-type hemoglobin should be produced. The percentage of incorrect expression might be as low as 10%–15% or as high as 100% of the total hemoglobin, usually higher in homozygotes than in heterozygotes. The present case is a typical example of homozygous HPFH.
Abstract licence: CC BY-NC-SA
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