The association between duration of illness, body mass index and diabetic neuropathy of median and ulner nerve in Bikaner region

Introduction: Diabetes Mellitus (DM) is a chronic disorder of the metabolism of glucose, lipids and proteins caused by a defect in insulin action or secretion. This metabolic disorder is responsible for chronic complications that affect macro and microcirculation.The manifestations of microvascular complications are more frequently found in the eyes, kidneys, and nerves, and those of macrovascular disease, in heart, brain, and leg arteries. Chronic metabolic disorder diabetes mellitus is fast growing global problem with huge social, health and economic consequences. Materials and Methods: The study was planned in Physiology Department in close collaboration with Department of Medicine (Diabetic Section), Sardar Patel Medical College, Bikaner & Associated Group of Hospital. A total of 100 subjects for study from diabetic centre, were selected. Institutional ethical clearance was taken before commencement of study from ethical committee of Sardar Patel Medical College, Bikaner & Associated Group of Hospital, Bikaner. Control and subject were similar in sex and age. Results: We observed that Mean age in study group was 52.66 ± 10.86 while in control group mean age was 32.06 ± 14.08 and this difference was found statistically highly significant (P < 0.001). We observed that the mean FBS in study group was 101.63 ± 25.20 mg% wwhile in control group it was 97.52 ± 19.53 mg% and the difference was found statistically insignificant (P > 0.05). The mean median nerve in study group was 51.68 ± 4.01 m/s and in control group it was 57.64 ± 4.52 m/s and the difference was found statistically highly significant (P < 0.001) and mean value of ulnar nerve in study group was 53.56 ± 3.53 m/s and in control group it was 60.73 ± 5.99 m/s and the difference was found statistically highly significant (P < 0.001). Conclusion: In our study, we concluded that nerve conduction velocities decreases in median, ulnar diabetic patients as compared to control. Nerve conduction velocities also decrease with increasing age, increased duration of disease, increased BMI.

Abstract licence: CC BY-NC-SA

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