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Wolf′s isotopic response: Report of a case and review of literature

Rahul Mahajan, Dipankar De, Uma Nahar Saikia

Indian Journal of Dermatology · 2014

doi:10.4103/0019-5154.131401 (opens in a new tab)

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Abstract

"Wolf′s isotopic response" refers to the occurrence of a new dermatosis at the site of previously healed dermatosis. A number of factors including viral, neural, vascular, and immunologic factors have been implicated in the causation of this peculiar response but none has been proven conclusively. Here, we report a case where lichen planus developed at the site of dermatofibrosarcoma protruberans that had been previously treated with surgery and radiotherapy. We also put forth a hypothesis on the genesis of isotopic response considering the above mentioned factors.

Abstract licence: CC BY-NC-SA

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