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Hemophagocytic lymphohistiocytosis and Pelger-Huët anomaly associated with colchicine intoxication

Baris Malbora, Emine Polat, Sare Gulfem Akyuz

Hematology Reports · 2014

doi:10.4081/hr.2014.5356 (opens in a new tab)

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Abstract

Colchicine is frequently used in the treatment of familial Mediterranean fever (FMF). First symptoms of colchicine intoxication are gastrointestinal disturbances, such as abdominal cramps, diarrhea, pancytopenia and so on. Herein, we report a female FMF patient with pancytopenia and hemophagocytic lymphohitiocytosis (HLH), following colchicine intoxication for committing suicide. To our knowledge, this is the first reported case of a patient with HLH associated with colchicine intoxication.

Abstract licence: CC BY

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