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Evans’ syndrome following vaccination with ChAdOx1 nCoV-19 in a patient with new-onset localized scleroderma

Thilo Gambichler, Pia Nordmann, Dimitri Kasakovski and 2 more

Dermatology Reports · 2022

doi:10.4081/dr.2022.9470 (opens in a new tab)

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Abstract

Growing evidence suggests that COVID-19 vaccines can induce hematological conditions. Here, we report a case of Evans’ syndrome, a combination of immune thrombocytopenic purpura and autoimmune hemolytic anemia following administration of the ChAdOx1 nCoV-19 vaccine. The present case further supports the notion that COVID-19 vaccines can trigger in rare cases severe persistent autoimmune-mediated hematological conditions which may predominantly occur in patients with underlying autoimmune conditions.

Abstract licence: CC BY-NC

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