New chemical constituents of Ambrosia psilostachya

Phytochemical studies on the methanolic extract of Amrosia psilostachya, native to Manitoba, have resulted in the isolation of two new sterols, ambrosinal A (1) and ambrosinal B (2) along with a known sesquiterpene lactone, coronopilin (3).Spectroscopic methods were used to establish the structures of these new and known compounds.Single crystal X-ray diffraction studies on compound 3 were also performed.Compounds 1-2 exhibited moderate antibacterial activity against pathogenic bacteria while compound 3 was weakly active in glutathione Stransferase inhibition assay.

Abstract licence: CC BY

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