Development of planar electrodes for real-time electroporation / Planariųjų elektrodų modelis realiojo laiko elektroporacijos tyrimams

In this paper the concept of planar electrodes for real-time electroporation on a microscope stage is presented and the structure is analyzed using finite element method (FEM) analysis. A multiparametric investigation of the chip topology is performed in COMSOL Multiphysics environment to define the configuration of electrodes, electric field distribution and other electroporation parameters to ensure a homogeneous cell exposure. Based on the simulation results, an optimal electrode configuration, which is suitable for the investigation of the permeabilization thresholds during electroporation, is proposed.

Abstract licence: CC BY

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