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Directed aromatic functionalization in natural-product synthesis: Fredericamycin A, nothapodytine B, and topopyrones B and D

Charles Dylan Turner, Marco A. Ciufolini

Beilstein Journal of Organic Chemistry · 2011

doi:10.3762/bjoc.7.171 (opens in a new tab)

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Abstract

This is a review of our efforts toward the synthesis of a group of natural products that display noteworthy biological activity: Fredericamycin A, nothapodytine B, and topopyrones B and D. In each case, directed aromatic functionalization methodology greatly facilitated the assembly of the key molecular subunits.

Abstract licence: CC BY

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