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A surprising new route to 4-nitro-3-phenylisoxazole

Henning Hopf, Aboul-fetouh E. Mourad, Peter G. Jones

Beilstein Journal of Organic Chemistry · 2010

doi:10.3762/bjoc.6.68 (opens in a new tab)

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Abstract

A one-pot synthesis of 4-nitro-3-phenylisoxazole has been carried out by treatment of cinnamyl alcohol dissolved in acetic acid with sodium nitrite; in addition, 4-phenyl-3-furoxanmethanol was obtained in 40% yield.

Abstract licence: CC BY

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