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A recent overview on the synthesis of 1,4,5-trisubstituted 1,2,3-triazoles

Pezhman Shiri, Ali Mohammad Amani, Thomas Mayer-Gall

Beilstein Journal of Organic Chemistry · 2021

doi:10.3762/bjoc.17.114 (opens in a new tab)

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Abstract

Diverse strategies for the efficient and attractive synthesis of a wide variety of relevant 1,4,5-trisubstituted 1,2,3-triazole molecules are reported. The synthesis of this category of diverse fully functionalized 1,2,3-triazoles has become a necessary and unique research subject in modern synthetic organic key transformations in academia, pharmacy, and industry. The current review aims to cover a wide literature survey of numerous synthetic strategies. Recent reports (2017–2021) in the field of 1,4,5-trisubstituted 1,2,3-triazoles are emphasized in this current review.

Abstract licence: CC BY

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