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Synthesis of (macro)heterocycles by consecutive/repetitive isocyanide-based multicomponent reactions

Angélica de Fátima S. Barreto, Carlos Kleber Z. Andrade

Beilstein Journal of Organic Chemistry · 2019

doi:10.3762/bjoc.15.88 (opens in a new tab)

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Abstract

Isocyanide-based multicomponent reactions are a versatile tool in the synthesis of heterocycles. This review describes recently developed approaches based on the combination of consecutive or repetitive isocyanide-based multicomponent reactions for the synthesis of structurally diverse heterocycles. These strategies have also allowed the synthesis of a plethora of macroheterocycles in a reduced number of steps.

Abstract licence: CC BY

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