Selectivity in multiple multicomponent reactions: types and synthetic applications
Ouldouz Ghashghaei, Francesca Seghetti, Rodolfo Lavilla
Beilstein Journal of Organic Chemistry · 2019
doi:10.3762/bjoc.15.46 (opens in a new tab)
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Abstract
Multiple multicomponent reactions reach an unparalleled level of connectivity, leading to highly complex adducts. Usually, only one type of transformation involving the same set of reactants takes place. However, in some occasions this is not the case. Selectivity issues then arise, and different scenarios are analyzed. The structural pattern of the reactants, the reaction design and the experimental conditions are the critical factors dictating selectivity in these processes.
Abstract licence: CC BY
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