Diosgenyl 2-amino-2-deoxy-β-D-galactopyranoside: synthesis, derivatives and antimicrobial activity
Henryk Myszka, Patrycja Sokołowska, Agnieszka Cieślińska and 4 more
Beilstein Journal of Organic Chemistry · 2017
doi:10.3762/bjoc.13.227 (opens in a new tab)
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Abstract
The synthesis of diosgenyl 2-amino-2-deoxy-β-D-galactopyranoside is presented for the first time. This synthetic saponin was transformed into its hydrochloride as well as N-acyl, 2-ureido, N-alkyl, and N,N-dialkyl derivatives. Antifungal and antibacterial studies show that some of the obtained compounds are active against Gram-positive bacteria and Candida type fungi.
Abstract licence: CC BY
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