The gut microbiome: scourge, sentinel or spectator?

The gut microbiota consists of trillions of prokaryotes that reside in the intestinal mucosa. This long-established commensalism indicates that these microbes are an integral part of the eukaryotic host. Recent research findings have implicated the dynamics of microbial function in setting thresholds for many physiological parameters. Conversely, it has been convincingly argued that dysbiosis, representing microbial imbalance, may be an important underlying factor that contributes to a variety of diseases, inside and outside the gut. This review discusses the latest findings, including enterotype classification, changes brought on by dysbiosis, gut inflammation, and metabolic mediators in an attempt to underscore the importance of the gut microbiota for human health. A cautiously optimistic idea is taking hold, invoking the gut microbiota as a medium to track, target and treat a plethora of diseases.

Abstract licence: CC BY-NC

• Communication of gut microbiota and brain via immune and neuroendocrine signaling · 2023

• Nutrition and cognitive health: A life course approach · 2023

• The role of short-chain fatty acids in the interplay between gut microbiota and diet in cardio-metabolic health · 2021

• Rebuilding the Gut Microbiota Ecosystem · 2018

• Dysbiotic Events in Gut Microbiota: Impact on Human Health · 2014

A person counts once a day per paper. We keep no cookie and no address: a reader is a hash that changes every day. Any month under five reads shows no number.