Selectivity/Specificity Improvement Strategies in Surface-Enhanced Raman Spectroscopy Analysis
Feng Wang, Shiyu Cao, Ruxia Yan and 3 more
Sensors · 2017
doi:10.3390/s17112689 (opens in a new tab)
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Abstract
Surface-enhanced Raman spectroscopy (SERS) is a powerful technique for the discrimination, identification, and potential quantification of certain compounds/organisms. However, its real application is challenging due to the multiple interference from the complicated detection matrix. Therefore, selective/specific detection is crucial for the real application of SERS technique. We summarize in this review five selective/specific detection techniques (chemical reaction, antibody, aptamer, molecularly imprinted polymers and microfluidics), which can be applied for the rapid and reliable selective/specific detection when coupled with SERS technique.
Abstract licence: CC BY
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