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Biomarker Discovery by Novel Sensors Based on Nanoproteomics Approaches

Manuel Fuentes, Alberto Orfao, María González-González and 4 more

Sensors · 2012

doi:10.3390/s120202284 (opens in a new tab)

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Abstract

During the last years, proteomics has facilitated biomarker discovery by coupling high-throughput techniques with novel nanosensors. In the present review, we focus on the study of label-based and label-free detection systems, as well as nanotechnology approaches, indicating their advantages and applications in biomarker discovery. In addition, several disease biomarkers are shown in order to display the clinical importance of the improvement of sensitivity and selectivity by using nanoproteomics approaches as novel sensors.

Abstract licence: CC BY

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