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Nanomaterials-Based Colorimetric Immunoassays

Lin Liu, Yuanqiang Hao, Dehua Deng and 1 more

Nanomaterials · 2019

doi:10.3390/nano9030316 (opens in a new tab)

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Abstract

Colorimetric immunoassays for tumor marker detection have attracted considerable attention due to their simplicity and high efficiency. With the achievements of nanotechnology and nanoscience, nanomaterials-based colorimetric immunoassays have been demonstrated to be promising alternatives to conventional colorimetric enzyme-linked immunoassays. This review is focused on the progress in colorimetric immunoassays with the signal amplification of nanomaterials, including nanomaterials-based artificial enzymes to catalyze the chromogenic reactions, analyte-induced aggregation or size/morphology change of nanomaterials, nanomaterials as the carriers for loading enzyme labels, and chromogenic reactions induced by the constituent elements released from nanomaterials.

Abstract licence: CC BY

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