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Oligonucleotide Labelling Using a Fluorogenic “Click” Reaction with a Hemicarboxonium Salt

Corinne Payrastre, Jean-Marc Escudier, Andreea Muntean and 2 more

Molecules · 2013

doi:10.3390/molecules181012966 (opens in a new tab)

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Abstract

Two fluorescent streptocyanine labelled oligonucleotides have been synthesized by a simple “click” reaction between a non-fluorescent hemicarboxonium salt and aminoalkyl functionalized thymidines within the oligonucleotide and their spectrophotometric properties have been studied.

Abstract licence: CC BY

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