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Synthesis of γ-Nitro Aliphatic Methyl Esters Via Michael Additions Promoted by Microwave Irradiation

Francisco D. Díaz-Coutiño, Jaime Escalante

Molecules · 2009

doi:10.3390/molecules14041595 (opens in a new tab)

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Abstract

A simple and efficient protocol has been developed for the direct synthesis of γ-nitrobutyric acid methyl esters under microwave irradiation. This methodology reduces reaction times from days to minutes, compared to conventional conditions. Additionally, these conditions increased yields and provided cleaner reactions.

Abstract licence: CC BY

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