A New Cytotoxic Pregnanone from Calotropis gigantea
Mao-Yuan Wang, Zhu-Nian Wang, Wen-Li Mei and 2 more
Molecules · 2008
doi:10.3390/molecules13123033 (opens in a new tab)
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Abstract
A new pregnanone, named calotropone (1), was isolated from the EtOH extract of the roots of Calotropis gigantea L. together with a known cardiac glycoside. The structures were elucidated by a study of their physical and spectral data. Compounds 1 and 2 displayed inhibitory effects towards chronic myelogenous leukemia K562 and human gastric cancer SGC-7901 cell lines.
Abstract licence: CC BY
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