Acylated Aminooligosaccharides with Inhibitory Effects against α-Amylase from Streptomyces sp. HO1518
Hai-Li Liu, Heng-Chao E, Ding-An Xie and 3 more
Marine Drugs · 2018
doi:10.3390/md16110403 (opens in a new tab)
We email you when a new notice or a question about this paper appears.
Abstract
Five new acylated aminooligosaccharides (<b>1</b>–<b>5</b>), together with one known related analogue (<b>6</b>), were isolated from <i>Streptomyces </i>sp. HO1518. Their structure was identified by extensive spectroscopic analysis, including 1D and 2D NMR data and high resolution electrospray ionization mass spectrometry (HRESIMS), and by comparison with those reported in the literature. All of the new compounds showed more promising porcine pancreatic <i>α</i>-amylase (PPA) inhibitory activities than the clinical drug acarbose, indicating them as potential pharmaceutical drug leads toward type II diabetes.
Abstract licence: CC BY
Reads
Read by people on this page
None yet.
Checked or read by AI through naulon
None yet.
A person counts once a day per paper. We keep no cookie and no address: a reader is a hash that changes every day. Any month under five reads shows no number.
Are you an author?
Is this your paper?
Claim it to add your note and be paid when agents cite it. Free.