Sterols from the Octocoral Nephthea columnaris
Ta-Yuan Whuang, Hong-Chieh Tsai, Yin-Di Su and 2 more
Marine Drugs · 2017
doi:10.3390/md15070212 (opens in a new tab)
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Abstract
Two new sterols, columnaristerols B (1) and C (2), along with two known analogues, 5,6-epoxylitosterol (3) and litosterol (4), were obtained from the octocoral Nephthea columnaris. The structures of new sterols 1 and 2 were elucidated by using spectroscopic methods and comparing the spectroscopic data with those of known related metabolites. Sterol 3 was found to suppress superoxide anion production and elastase secretion by human neutrophils.
Abstract licence: CC BY
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