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Terpenoids from the Octocorals Menella sp. (Plexauridae) and Lobophytum crassum (Alcyonacea)

Zhi-Hong Wen, Tsong-Long Hwang, Yueh-Hsiung Kuo and 6 more

Marine Drugs · 2012

doi:10.3390/md10020427 (opens in a new tab)

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Abstract

A new germacrane-type sesquiterpenoid, menelloide E (1), and a new cembrane-type diterpenoid, lobocrassin F (2), were isolated from the octocorals Menella sp. and Lobophytum crassum, respectively. The structures of terpenoids 1 and 2 were determined by spectroscopic and chemical methods and compound 2 was found to display a significant inhibitory effect on the release of elastase by human neutrophils.

Abstract licence: CC BY

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