1-(4-Hexylbenzoyl)-3-methylthiourea
Ruswanto Ruswanto, Richa Mardianingrum, Tresna Lestari and 2 more
Molbank · 2018
doi:10.3390/m1005 (opens in a new tab)
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Abstract
The 1-(4-hexylbenzoyl)-3-methylthiourea compound has been successfully synthesized by reacting 4-hexylbenzoyl chloride and 1-methylthiourea via the reflux method using a triethylamine catalyst. The 1-(4-hexylbenzoyl)-3-methylthiourea compound was identified by UV-visible, FT-IR, 13C/1H-NMR and Mass spectrophotometry. From the activity test on four cancer cell lines (HeLa, T47D, WiDr and MCF7 cell), it could be seen that it had better activity on four cancer cells than the control, hydroxyurea.
Abstract licence: CC BY
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