Sequencing and Analysis of the Genome of Propionibacterium freudenreichii T82 Strain: Importance for Industry
Kamil Piwowarek, Edyta Lipińska, Elżbieta Hać-Szymańczuk and 2 more
Biomolecules · 2020
doi:10.3390/biom10020348 (opens in a new tab)
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Abstract
The genome of <i>Propionibacterium freudenreichii</i> ssp. <i>freudenreichii</i> T82, which has a chromosome containing 2,585,340 nucleotides with 67.3% GC content (guanine-cytosine content), is described in this paper. The total number of genes is 2308, of which 2260 are protein-coding genes and 48 are RNA genes. According to the genome analysis and the obtained results, the T82 strain can produce various compounds such as propionic acid, trehalose, glycogen, and B group vitamins (e.g., B6, B9, and B12). From protein-coding sequences (CDSs), genes related to stress adaptation, biosynthesis, metabolism, transport, secretion, and defense machinery were detected. In the genome of the T82 strain, sequences corresponding to the CRISPR loci (Clustered Regularly Interspaced Short Palindromic Repeats), antibiotic resistance, and restriction−modification system were found.
Abstract licence: CC BY
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