Synthesis of Novel Quinazoline Derivatives via Pyrimidine ortho-Quinodimethane
A. Herrera Fernández, R. MartÃÂnez-Alvarez, M. Chioua and 2 more
Molecules · 2002
doi:10.3390/70700507 (opens in a new tab)
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Abstract
The [4+2] cycloaddition between 2,4-diphenylpyrimidine ortho-quinodimethane and dimethyl acetylenedicarboxylate leads to 2,4-diphenylquinazoline-6,7-dicarboxylate (6). 2,4-Diphenylfuro[3,4-g]quinazoline-6,8-dione (7) is also obtained by basic hydrolysis of compound 6, followed by the closure of the resulting diacid in acetic anhydride.
Abstract licence: CC BY
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